Can B200 192GB SXM run Mixtral-8x7B-Instruct-v0.1?

NVIDIA · 192 GB HBM3e · 8000 GB/s bandwidth · Mistral · 46.7B (active 12.9B) · MoE · model ctx up to 32K

Yes — the B200 192GB SXM (192 GB HBM3e) can run Mixtral-8x7B-Instruct-v0.1. At Q4 with the default 8K context it needs ≈ 29.27 GB VRAM (weights 25.69 GB + KV cache 2.58 GB + 1 GB runtime overhead), which fits within 192 GB. Decode at Q4/8K: ≈ 394.6 tok/s (estimated, batch 1). FP16 (≈ 96.98 GB) also fits, at ≈ 108.5 tok/s (estimated). Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

Quant	Context	VRAM needed	Fits?	tok/s (decode)
Q4	4K	27.98 GB	Yes	394.6 est.
Q4	8K default	29.27 GB	Yes	394.6 est.
Q4	32K	37.01 GB	Yes	394.6 est.
FP16	4K	95.69 GB	Yes	108.5 est.
FP16	8K default	96.98 GB	Yes	108.5 est.
FP16	32K	104.72 GB	Yes	108.5 est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

Quant	Weights	KV cache	Overhead	Total needed	B200 192GB SXM VRAM
Q4	25.69 GB	2.58 GB	1 GB	29.27 GB	192 GB
FP16	93.4 GB	2.58 GB	1 GB	96.98 GB	192 GB

Other GPUs that run Mixtral-8x7B-Instruct-v0.1

• MI300X 192GB — ≈261.5 tok/s Q4 est.
• H200 141GB SXM5 — ≈236.8 tok/s Q4 est.
• H100 80GB SXM5 — ≈165.3 tok/s Q4 est.
• Gaudi 3 128GB — ≈161.6 tok/s Q4 est.
• A100 80GB SXM4 — ≈100.6 tok/s Q4 est.
• RTX 5090 32GB — ≈88.4 tok/s Q4 est.
• RTX 6000 Ada 48GB — ≈47.4 tok/s Q4 est.
• L40S 48GB — ≈42.6 tok/s Q4 est.

All GPUs for Mixtral-8x7B-Instruct-v0.1 →

Other models for the B200 192GB SXM

• gemma-3-1b-it — ≈5000 tok/s Q4 est.
• Qwen3-0.6B — ≈5000 tok/s Q4 est.
• Llama-3.2-1B-Instruct — ≈4242.4 tok/s Q4 est.
• Qwen3-1.7B — ≈2545.5 tok/s Q4 est.
• Qwen3-30B-A3B — ≈1697.0 tok/s Q4 est.
• Qwen3-Coder-30B-A3B-Instruct — ≈1697.0 tok/s Q4 est.
• GLM-4.7-Flash — ≈1697.0 tok/s Q4 est.
• Qwen3-30B-A3B-Instruct-2507 — ≈1697.0 tok/s Q4 est.

All models on the B200 192GB SXM →