Can Titan V 12GB run Qwen3-Next-80B-A3B-Instruct?

NVIDIA · 12 GB HBM2 · 652.8 GB/s bandwidth · Alibaba · 81.3B (active 3B) · MoE · model ctx up to 256K

CUDA

No — Qwen3-Next-80B-A3B-Instruct at Q4 needs ≈ 45.75 GB even at 4K context, beyond the Titan V 12GB's 12 GB HBM2. It would only run with heavy CPU/disk offload. Decode at Q4/8K: ≈ 27.1 tok/s (estimated, batch 1). FP16 needs ≈ 163.67 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

Quant	Context	VRAM needed	Fits?	tok/s (decode)
Q4	4K	45.75 GB	No	27.1 ± est.
Q4	8K default	45.79 GB	No	27.1 ± est.
Q4	32K	46.02 GB	No	26.8 ± est.
FP16	4K	163.64 GB	No	—
FP16	8K default	163.67 GB	No	—
FP16	32K	163.9 GB	No	—

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

Quant	Weights	KV cache	Overhead	Total needed	Titan V 12GB VRAM
Q4	44.72 GB	0.08 GB	1 GB	45.79 GB	12 GB
FP16	162.6 GB	0.08 GB	1 GB	163.67 GB	12 GB

Other GPUs that run Qwen3-Next-80B-A3B-Instruct

• B200 192GB SXM — ≈1697.0 tok/s Q4 est.
• MI300X 192GB — ≈1124.2 tok/s Q4 est.
• H200 141GB SXM5 — ≈1018.2 tok/s Q4 est.
• H100 80GB SXM5 — ≈710.6 tok/s Q4 est.
• Gaudi 3 128GB — ≈694.9 tok/s Q4 est.
• A100 80GB SXM4 — ≈432.5 tok/s Q4 est.
• RTX 6000 Ada 48GB — ≈203.6 tok/s Q4 est.
• L40S 48GB — ≈183.3 tok/s Q4 est.

All GPUs for Qwen3-Next-80B-A3B-Instruct →

Other models for the Titan V 12GB

• MiniCPM5-1B — ≈384.6 tok/s Q4 est.
• Qwen3.5-2B — ≈207.7 tok/s Q4 est.
• DeepSeek-R1-0528-Qwen3-8B-layer-mix-bpw-3.8-mlx — ≈180.6 tok/s Q4 est.
• Llama-3.2-3B-Instruct — ≈129.8 tok/s Q4 est.
• Qwen3-4B-Instruct-2507 — ≈103.9 tok/s Q4 est.
• NVIDIA-Nemotron-3-Nano-4B-BF16 — ≈103.9 tok/s Q4 est.
• Qwen3-4B-Thinking-2507 — ≈103.9 tok/s Q4 est.
• gemma-4-E2B-it — ≈81.5 tok/s Q4 est.

All models on the Titan V 12GB →