Can RTX 6000 Ada 48GB run Qwen3-Next-80B-A3B-Instruct?

NVIDIA · 48 GB GDDR6 · 960 GB/s bandwidth · Alibaba · 81.3B (active 3B) · MoE · model ctx up to 256K

No — Qwen3-Next-80B-A3B-Instruct at Q4 needs ≈ 46.02 GB even at 4K context, beyond the RTX 6000 Ada 48GB's 48 GB GDDR6. It would only run with heavy CPU/disk offload. Decode at Q4/8K: ≈ 624.8 tok/s (estimated, batch 1). FP16 needs ≈ 164.2 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

Quant	Context	VRAM needed	Fits?	tok/s (decode)
Q4	4K	46.02 GB	No	633.0 est.
Q4	8K default	46.32 GB	No	624.8 est.
Q4	32K	48.12 GB	No	578.9 est.
FP16	4K	163.9 GB	No	13.7 est.
FP16	8K default	164.2 GB	No	13.7 est.
FP16	32K	166.0 GB	No	13.4 est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

Quant	Weights	KV cache	Overhead	Total needed	RTX 6000 Ada 48GB VRAM
Q4	44.72 GB	0.6 GB	1 GB	46.32 GB	48 GB
FP16	162.6 GB	0.6 GB	1 GB	164.2 GB	48 GB

Other GPUs that run Qwen3-Next-80B-A3B-Instruct

• B200 192GB SXM — ≈1697.0 tok/s Q4 est.
• MI300X 192GB — ≈1124.2 tok/s Q4 est.
• H200 141GB SXM5 — ≈1018.2 tok/s Q4 est.
• H100 80GB SXM5 — ≈710.6 tok/s Q4 est.
• Gaudi 3 128GB — ≈694.9 tok/s Q4 est.
• A100 80GB SXM4 — ≈432.5 tok/s Q4 est.
• Mac Studio M3 Ultra 96GB — ≈173.7 tok/s Q4 est.
• Mac Studio M2 Ultra 192GB — ≈169.7 tok/s Q4 est.

All GPUs for Qwen3-Next-80B-A3B-Instruct →

Other models for the RTX 6000 Ada 48GB

• Qwen3-0.6B — ≈763.6 tok/s Q4 est.
• gemma-3-1b-it — ≈610.9 tok/s Q4 est.
• Llama-3.2-1B-Instruct — ≈509.1 tok/s Q4 est.
• Qwen3-1.7B — ≈305.5 tok/s Q4 est.
• Qwen3-30B-A3B — ≈203.6 tok/s Q4 est.
• Qwen3-Coder-30B-A3B-Instruct — ≈203.6 tok/s Q4 est.
• GLM-4.7-Flash — ≈203.6 tok/s Q4 est.
• Qwen3-30B-A3B-Instruct-2507 — ≈203.6 tok/s Q4 est.

All models on the RTX 6000 Ada 48GB →