Yes — the MacBook Pro M1 Max 64GB (64 GB LPDDR5) can run Qwen3-Next-80B-A3B-Instruct. At Q4 with the default 8K context it needs ≈ 45.79 GB VRAM (weights 44.72 GB + KV cache 0.08 GB + 1 GB runtime overhead), which fits within 64 GB. Decode at Q4/8K: ≈ 84.8 tok/s (estimated, batch 1). FP16 needs ≈ 163.67 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology. Buy MacBook Pro M1 Max 64GB on Amazon →
Fit & speed by quant and context
Quant
Context
VRAM needed
Fits?
tok/s (decode)
Q4
4K
45.75 GB
Yes
84.8±est.
Q4
8K default
45.79 GB
Yes
84.8±est.
Q4
32K
46.02 GB
Yes
84.8±est.
FP16
4K
163.64 GB
No
10.2±est.
FP16
8K default
163.67 GB
No
10.2±est.
FP16
32K
163.9 GB
No
10.2±est.
Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).