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Can H200 141GB SXM5 run Mistral-Medium-3.5-128B?

NVIDIA · 141 GB HBM3e · 4800 GB/s bandwidth · Mistral · 128.0B · model ctx up to 256K

Yes — the H200 141GB SXM5 (141 GB HBM3e) can run Mistral-Medium-3.5-128B. At Q4 with the default 8K context it needs ≈ 97.0 GB VRAM (weights 70.4 GB + KV cache 25.6 GB + 1 GB runtime overhead), which fits within 141 GB. Decode at Q4/8K: ≈ 23.9 tok/s (estimated, batch 1). FP16 needs ≈ 282.6 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

QuantContextVRAM neededFits?tok/s (decode)
Q44K84.2 GBYes23.9 est.
Q48K default97.0 GBYes23.9 est.
Q432K173.8 GBNo44.9 est.
FP164K269.8 GBNo5.1 est.
FP168K default282.6 GBNo4.7 est.
FP1632K359.4 GBNo2.9 est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

QuantWeightsKV cacheOverheadTotal neededH200 141GB SXM5 VRAM
Q470.4 GB25.6 GB1 GB97.0 GB141 GB
FP16256.0 GB25.6 GB1 GB282.6 GB141 GB

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