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Can Ryzen AI Max+ 395 64GB run Qwen3.6-35B-A3B-NVFP4?

AMD · 48 GB LPDDR5X · 215 GB/s bandwidth · nvidia · 21.6B (active 21.6B) · MoE · model ctx up to NoneK

✅ Yes — Ryzen AI Max+ 395 64GB (48 GB) can run Qwen3.6-35B-A3B-NVFP4 at Q4 (8K)
VRAM: 17.2 GB needed of 48 GB
Speed: ~10.2 tok/s (estimated)
BB · GoodComposite score: VRAM headroom × 0.5 + tok/s speed × 0.5. Q4 @ 8K context.
ROCM
Estimates from memory-bandwidth formula; rows marked "measured" override. Methodology.

Fit & speed by quant and context

QuantContextVRAM neededFits?tok/s (decode)
Q44K15.04 GBYes10.2 ± est.
Q48K default17.2 GBYes10.2 ± est.
Q432K30.16 GBYes10.2 ± est.
FP164K46.36 GBYes2.8 ± est.
FP168K default48.52 GBNo4.9 ± est.
FP1632K61.48 GBNo3.0 ± est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

QuantWeightsKV cacheOverheadTotal neededRyzen AI Max+ 395 64GB VRAM
Q411.88 GB4.32 GB1 GB17.2 GB48 GB
FP1643.2 GB4.32 GB1 GB48.52 GB48 GB

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