No — DeepSeek-V4-Flash at Q4 needs ≈ 88.12 GB even at 4K context, beyond the Ryzen AI Max+ 395 64GB's 48 GB LPDDR5X. It would only run with heavy CPU/disk offload. Decode at Q4/8K: ≈ 8.9 tok/s (estimated, batch 1). FP16 needs ≈ 317.52 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.
Fit & speed by quant and context
Quant
Context
VRAM needed
Fits?
tok/s (decode)
Q4
4K
88.12 GB
No
8.9est.
Q4
8K default
88.28 GB
No
8.9est.
Q4
32K
89.25 GB
No
8.7est.
FP16
4K
317.36 GB
No
—
FP16
8K default
317.52 GB
No
—
FP16
32K
318.5 GB
No
—
Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).