MI300X 192GB vs Titan Xp 12GB for Local LLMs

The MI300X 192GB has about 867% more memory bandwidth (5,300 vs 548 GB/s). Batch-1 decode tracks bandwidth closely, so a model that fits both cards should decode roughly 867% faster on the MI300X 192GB. The MI300X 192GB fits more of the catalog at Q4/8K — 57 vs 18 of 69 models (192 vs 12 GB VRAM). Largest model that fits the MI300X 192GB but not the Titan Xp 12GB: MiMo-V2.5 (310.0B). MSRP is $15,000 for the MI300X 192GB vs $1,200 for the Titan Xp 12GB. MSRP is a launch list price, not live retail — Amazon prices move; click through for the current price. Not retail-shoppable: MI300X 192GB (datacenter-class; cloud rental is the realistic way to use it). In the Q4/8K head-to-head below (41 shared models), the MI300X 192GB posts the higher tok/s in 41 rows vs 0. Methodology.

Spec comparison

	MI300X 192GB	Titan Xp 12GB
Vendor	AMD	NVIDIA
VRAM	192 GB	12 GB
Memory type	HBM3	GDDR5X
Memory bandwidth	5,300 GB/s	548 GB/s
TDP	750 W	250 W
MSRP (list)	$15,000	$1,200
Buy	—	Search Amazon (affiliate)

MSRP is the launch list price, not live retail. Buy links are Amazon affiliate links — the price after you click is the live price.

Q4 / 8K head-to-head — top 15 of 41 shared models

Model	Params (B)	MI300X 192GB tok/s	MI300X 192GB fits	Titan Xp 12GB tok/s	Titan Xp 12GB fits	Winner
MiniCPM5-1B	1.08	3122.9 est.	Yes	322.9 est.	Yes	MI300X 192GB
Qwen3.5-2B	2.0	1686.4 est.	Yes	174.4 est.	Yes	MI300X 192GB
DeepSeek-R1-0528-Qwen3-8B-layer-mix-bpw-3.8-mlx	2.3	1466.4 est.	Yes	151.6 est.	Yes	MI300X 192GB
Qwen3.6-35B-A3B	36.0	1124.2 est.	Yes	109.2 est.	No	MI300X 192GB
Qwen3.5-35B-A3B	34.7	1124.2 est.	Yes	117.2 est.	No	MI300X 192GB
GLM-4.7-Flash	31.2	1124.2 est.	Yes	135.3 est.	No	MI300X 192GB
Qwen3-30B-A3B-Instruct-2507	30.5	1124.2 est.	Yes	141.0 est.	No	MI300X 192GB
Nemotron-3-Nano-Omni-30B-A3B-Reasoning-BF16	30.0	1124.2 est.	Yes	155.0 est.	No	MI300X 192GB
Qwen3-Coder-Next	79.7	1124.2 est.	Yes	23.6 est.	No	MI300X 192GB
Ornith-1.0-35B	35.0	1124.2 est.	Yes	109.6 est.	No	MI300X 192GB
Qwen3-Next-80B-A3B-Instruct	81.3	1124.2 est.	Yes	22.7 est.	No	MI300X 192GB
qwen35b-a3b-fable-sft-abliterated	34.7	1124.2 est.	Yes	111.3 est.	No	MI300X 192GB
Llama-3.2-3B-Instruct	3.2	1054.0 est.	Yes	109.0 est.	Yes	MI300X 192GB
gpt-oss-20b	21.5	936.9 est.	Yes	216.2 est.	No	MI300X 192GB
gemma-4-26B-A4B-it	25.2	887.6 est.	Yes	154.1 est.	No	MI300X 192GB

est. = bandwidth-based estimate; measured = curated real benchmark that overrides the estimate. Fits = weights + KV(8K) + 1 GB overhead ≤ 95% of VRAM.

Fit coverage at Q4 / 8K

	MI300X 192GB	Titan Xp 12GB
Catalog models that fit	57 of 69	18 of 69
Largest exclusive fit	MiMo-V2.5 (310.0B)	—

MI300X 192GB details → · Titan Xp 12GB details →