Ryzen AI Max+ 395 64GB vs Mac mini M4 Pro 64GB for Local LLMs

The Mac mini M4 Pro 64GB has about 27% more memory bandwidth (273 vs 215 GB/s). Batch-1 decode tracks bandwidth closely, so a model that fits both cards should decode roughly 27% faster on the Mac mini M4 Pro 64GB. The Mac mini M4 Pro 64GB fits more of the catalog at Q4/8K — 44 vs 41 of 69 models (64 vs 48 GB VRAM). Largest model that fits the Mac mini M4 Pro 64GB but not the Ryzen AI Max+ 395 64GB: Qwen2.5-72B-Instruct (72.7B). MSRP is $1,500 for the Ryzen AI Max+ 395 64GB vs $2,199 for the Mac mini M4 Pro 64GB. MSRP is a launch list price, not live retail — Amazon prices move; click through for the current price. In the Q4/8K head-to-head below (57 shared models), the Mac mini M4 Pro 64GB posts the higher tok/s in 55 rows vs 2. Methodology.

Spec comparison

	Ryzen AI Max+ 395 64GB	Mac mini M4 Pro 64GB
Vendor	AMD	Apple
VRAM	48 GB	64 GB
Memory type	LPDDR5X	LPDDR5X
Memory bandwidth	215 GB/s	273 GB/s
TDP	120 W	155 W
MSRP (list)	$1,500	$2,199
Buy	Search Amazon (affiliate)	Search Amazon (affiliate)

MSRP is the launch list price, not live retail. Buy links are Amazon affiliate links — the price after you click is the live price.

Q4 / 8K head-to-head — top 15 of 57 shared models

Model	Params (B)	Ryzen AI Max+ 395 64GB tok/s	Ryzen AI Max+ 395 64GB fits	Mac mini M4 Pro 64GB tok/s	Mac mini M4 Pro 64GB fits	Winner
MiniCPM5-1B	1.08	126.7 est.	Yes	160.9 est.	Yes	Mac mini M4 Pro 64GB
Qwen3.5-2B	2.0	68.4 est.	Yes	86.9 est.	Yes	Mac mini M4 Pro 64GB
gpt-oss-120b	120.4	37.9 est.	No	85.5 est.	No	Mac mini M4 Pro 64GB
DeepSeek-R1-0528-Qwen3-8B-layer-mix-bpw-3.8-mlx	2.3	59.5 est.	Yes	75.5 est.	Yes	Mac mini M4 Pro 64GB
Mistral-Small-4-119B-2603	119.0	30.2 est.	No	68.1 est.	No	Mac mini M4 Pro 64GB
Qwen3.6-35B-A3B	36.0	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
Qwen3.5-35B-A3B	34.7	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
GLM-4.7-Flash	31.2	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
Qwen3-30B-A3B-Instruct-2507	30.5	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
Nemotron-3-Nano-Omni-30B-A3B-Reasoning-BF16	30.0	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
Qwen3-Coder-Next	79.7	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
Ornith-1.0-35B	35.0	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
Qwen3-Next-80B-A3B-Instruct	81.3	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
qwen35b-a3b-fable-sft-abliterated	34.7	45.6 est.	Yes	57.9 est.	Yes	Mac mini M4 Pro 64GB
Llama-3.2-3B-Instruct	3.2	42.8 est.	Yes	54.3 est.	Yes	Mac mini M4 Pro 64GB

est. = bandwidth-based estimate; measured = curated real benchmark that overrides the estimate. Fits = weights + KV(8K) + 1 GB overhead ≤ 95% of VRAM.

Fit coverage at Q4 / 8K

	Ryzen AI Max+ 395 64GB	Mac mini M4 Pro 64GB
Catalog models that fit	41 of 69	44 of 69
Largest exclusive fit	—	Qwen2.5-72B-Instruct (72.7B)

Ryzen AI Max+ 395 64GB details → · Mac mini M4 Pro 64GB details →