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RTX A6000 48GB vs RTX 5080 16GB for Local LLMs

The RTX 5080 16GB has about 25% more memory bandwidth (960 vs 768 GB/s). Batch-1 decode tracks bandwidth closely, so a model that fits both cards should decode roughly 25% faster on the RTX 5080 16GB. The RTX A6000 48GB fits more of the catalog at Q4/8K — 39 vs 25 of 61 models (48 vs 16 GB VRAM). Largest model that fits the RTX A6000 48GB but not the RTX 5080 16GB: Qwen3-Coder-Next (79.7B). MSRP is $4,500 for the RTX A6000 48GB vs $999 for the RTX 5080 16GB. MSRP is a launch list price, not live retail — Amazon prices move; click through for the current price. In the Q4/8K head-to-head below (44 shared models), the RTX 5080 16GB posts the higher tok/s in 38 rows vs 6. Methodology.

Spec comparison

RTX A6000 48GBRTX 5080 16GB
VendorNVIDIANVIDIA
VRAM48 GB16 GB
Memory typeGDDR6GDDR7
Memory bandwidth768 GB/s960 GB/s
TDP300 W360 W
MSRP (list)$4,500$999
BuySearch Amazon (affiliate)NVIDIA GeForce RTX 5080 Founders Edition (affiliate) · More listings

MSRP is the launch list price, not live retail. Buy links are Amazon affiliate links — the price after you click is the live price.

Q4 / 8K head-to-head — top 15 of 44 shared models

ModelParams (B)RTX A6000 48GB tok/sRTX A6000 48GB fitsRTX 5080 16GB tok/sRTX 5080 16GB fitsWinner
Qwen3-0.6B0.8610.9 est.Yes763.6 est.YesRTX 5080 16GB
gemma-3-1b-it1.0488.7 est.Yes610.9 est.YesRTX 5080 16GB
Llama-3.2-1B-Instruct1.2407.3 est.Yes509.1 est.YesRTX 5080 16GB
Qwen3-Next-80B-A3B-Instruct81.3499.8 est.No69.4 est.NoRTX A6000 48GB
Qwen3-30B-A3B30.5162.9 est.Yes440.9 est.NoRTX 5080 16GB
Qwen3-Coder-30B-A3B-Instruct30.5162.9 est.Yes440.9 est.NoRTX 5080 16GB
Qwen3-30B-A3B-Instruct-250730.5162.9 est.Yes440.9 est.NoRTX 5080 16GB
GLM-4.7-Flash31.2162.9 est.Yes423.2 est.NoRTX 5080 16GB
Qwen3-1.7B2.0244.4 est.Yes305.5 est.YesRTX 5080 16GB
gpt-oss-20b21.5135.8 est.Yes204.9 measuredYesRTX 5080 16GB
Llama-3.2-3B-Instruct3.2152.7 est.Yes190.9 est.YesRTX 5080 16GB
Mistral-7B-Instruct-v0.37.267.9 est.Yes163.6 measuredYesRTX 5080 16GB
Qwen3-Coder-Next79.7162.9 est.Yes72.1 est.NoRTX A6000 48GB
Phi-4-mini-instruct3.8128.6 est.Yes160.8 est.YesRTX 5080 16GB
Phi-4-mini-reasoning3.8128.6 est.Yes160.8 est.YesRTX 5080 16GB

est. = bandwidth-based estimate; measured = curated real benchmark that overrides the estimate. Fits = weights + KV(8K) + 1 GB overhead ≤ 95% of VRAM.

Fit coverage at Q4 / 8K

RTX A6000 48GBRTX 5080 16GB
Catalog models that fit39 of 6125 of 61
Largest exclusive fitQwen3-Coder-Next (79.7B)—

RTX A6000 48GB details → · RTX 5080 16GB details →