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Can V100 32GB SXM2 run Qwen2.5-72B-Instruct?

NVIDIA · 32 GB HBM2 · 900 GB/s bandwidth · Alibaba · 72.7B · model ctx up to 128K

❌ No — Qwen2.5-72B-Instruct Q4 needs 42.24 GB, card only has 32 GB
VRAM: 42.24 GB needed of 32 GB
Speed: ~12.2 tok/s (estimated)
FF · No FitComposite score: VRAM headroom × 0.5 + tok/s speed × 0.5. Q4 @ 8K context.
CUDA
Your GPU won't fit Qwen2.5-72B-Instruct, but runs these similar models: Qwen3-8B, gemma-4-26B-A4B-itor☁️ Rent on RunPod from ~$0.50/hr
Estimates from memory-bandwidth formula; rows marked "measured" override. Methodology.

Fit & speed by quant and context

QuantContextVRAM neededFits?tok/s (decode)
Q44K42.24 GBNo12.9 ± est.
Q48K default43.49 GBNo12.2 ± est.
Q432K50.99 GBNo8.9 ± est.
FP164K147.65 GBNo
FP168K default148.9 GBNo
FP1632K156.4 GBNo

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

QuantWeightsKV cacheOverheadTotal neededV100 32GB SXM2 VRAM
Q439.99 GB2.5 GB1 GB43.49 GB32 GB
FP16145.4 GB2.5 GB1 GB148.9 GB32 GB

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