Can MI300X 192GB run gpt-oss-120b?

AMD · 192 GB HBM3 · 5300 GB/s bandwidth · OpenAI · 120.4B (active 5.1B) · MoE · model ctx up to 128K

Yes — the MI300X 192GB (192 GB HBM3) can run gpt-oss-120b. At Q4 with the default 8K context it needs ≈ 68.24 GB VRAM (weights 66.22 GB + KV cache 1.02 GB + 1 GB runtime overhead), which fits within 192 GB. Decode at Q4/8K: ≈ 661.3 tok/s (estimated, batch 1). FP16 needs ≈ 242.82 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

Quant	Context	VRAM needed	Fits?	tok/s (decode)
Q4	4K	67.73 GB	Yes	661.3 est.
Q4	8K default	68.24 GB	Yes	661.3 est.
Q4	32K	71.3 GB	Yes	661.3 est.
FP16	4K	242.31 GB	No	326.2 est.
FP16	8K default	242.82 GB	No	324.9 est.
FP16	32K	245.88 GB	No	316.8 est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

Quant	Weights	KV cache	Overhead	Total needed	MI300X 192GB VRAM
Q4	66.22 GB	1.02 GB	1 GB	68.24 GB	192 GB
FP16	240.8 GB	1.02 GB	1 GB	242.82 GB	192 GB

Other GPUs that run gpt-oss-120b

• B200 192GB SXM — ≈998.2 tok/s Q4 est.
• H200 141GB SXM5 — ≈598.9 tok/s Q4 est.
• H100 80GB SXM5 — ≈418.0 tok/s Q4 est.
• Gaudi 3 128GB — ≈408.8 tok/s Q4 est.
• A100 80GB SXM4 — ≈254.4 tok/s Q4 est.
• Mac Studio M3 Ultra 96GB — ≈102.2 tok/s Q4 est.
• Mac Studio M2 Ultra 192GB — ≈79.7 tok/s Q4 measured
• MacBook Pro M4 Max 128GB — ≈68.1 tok/s Q4 est.

All GPUs for gpt-oss-120b →

Other models for the MI300X 192GB

• Qwen3-0.6B — ≈4215.9 tok/s Q4 est.
• gemma-3-1b-it — ≈3372.7 tok/s Q4 est.
• Llama-3.2-1B-Instruct — ≈2810.6 tok/s Q4 est.
• Qwen3-1.7B — ≈1686.4 tok/s Q4 est.
• Qwen3-30B-A3B — ≈1124.2 tok/s Q4 est.
• Qwen3-Coder-30B-A3B-Instruct — ≈1124.2 tok/s Q4 est.
• GLM-4.7-Flash — ≈1124.2 tok/s Q4 est.
• Qwen3-30B-A3B-Instruct-2507 — ≈1124.2 tok/s Q4 est.

All models on the MI300X 192GB →