Can MI300X 192GB run Qwen3-235B-A22B?

AMD · 192 GB HBM3 · 5300 GB/s bandwidth · Alibaba · 235.1B (active 22B) · MoE · model ctx up to 128K

Yes — the MI300X 192GB (192 GB HBM3) can run Qwen3-235B-A22B. At Q4 with the default 8K context it needs ≈ 134.71 GB VRAM (weights 129.31 GB + KV cache 4.4 GB + 1 GB runtime overhead), which fits within 192 GB. Decode at Q4/8K: ≈ 153.3 tok/s (estimated, batch 1). FP16 needs ≈ 475.6 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

Quant	Context	VRAM needed	Fits?	tok/s (decode)
Q4	4K	132.5 GB	Yes	153.3 est.
Q4	8K default	134.71 GB	Yes	153.3 est.
Q4	32K	147.91 GB	Yes	153.3 est.
FP16	4K	473.4 GB	No	19.8 est.
FP16	8K default	475.6 GB	No	19.6 est.
FP16	32K	488.8 GB	No	18.6 est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

Quant	Weights	KV cache	Overhead	Total needed	MI300X 192GB VRAM
Q4	129.31 GB	4.4 GB	1 GB	134.71 GB	192 GB
FP16	470.2 GB	4.4 GB	1 GB	475.6 GB	192 GB

Other GPUs that run Qwen3-235B-A22B

• B200 192GB SXM — ≈231.4 tok/s Q4 est.
• Mac Studio M2 Ultra 192GB — ≈23.1 tok/s Q4 est.

All GPUs for Qwen3-235B-A22B →

Other models for the MI300X 192GB

• Qwen3-0.6B — ≈4215.9 tok/s Q4 est.
• gemma-3-1b-it — ≈3372.7 tok/s Q4 est.
• Llama-3.2-1B-Instruct — ≈2810.6 tok/s Q4 est.
• Qwen3-1.7B — ≈1686.4 tok/s Q4 est.
• Qwen3-30B-A3B — ≈1124.2 tok/s Q4 est.
• Qwen3-Coder-30B-A3B-Instruct — ≈1124.2 tok/s Q4 est.
• GLM-4.7-Flash — ≈1124.2 tok/s Q4 est.
• Qwen3-30B-A3B-Instruct-2507 — ≈1124.2 tok/s Q4 est.

All models on the MI300X 192GB →