Can H200 141GB SXM5 run Qwen2.5-7B-Instruct?

NVIDIA · 141 GB HBM3e · 4800 GB/s bandwidth · Alibaba · 7.6B · model ctx up to 128K

Yes — the H200 141GB SXM5 (141 GB HBM3e) can run Qwen2.5-7B-Instruct. At Q4 with the default 8K context it needs ≈ 6.7 GB VRAM (weights 4.18 GB + KV cache 1.52 GB + 1 GB runtime overhead), which fits within 141 GB. Decode at Q4/8K: ≈ 401.9 tok/s (estimated, batch 1). FP16 (≈ 17.72 GB) also fits, at ≈ 110.5 tok/s (estimated). Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

Quant	Context	VRAM needed	Fits?	tok/s (decode)
Q4	4K	5.94 GB	Yes	401.9 est.
Q4	8K default	6.7 GB	Yes	401.9 est.
Q4	32K	11.26 GB	Yes	401.9 est.
FP16	4K	16.96 GB	Yes	110.5 est.
FP16	8K default	17.72 GB	Yes	110.5 est.
FP16	32K	22.28 GB	Yes	110.5 est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

Quant	Weights	KV cache	Overhead	Total needed	H200 141GB SXM5 VRAM
Q4	4.18 GB	1.52 GB	1 GB	6.7 GB	141 GB
FP16	15.2 GB	1.52 GB	1 GB	17.72 GB	141 GB

Other GPUs that run Qwen2.5-7B-Instruct

• B200 192GB SXM — ≈669.9 tok/s Q4 est.
• MI300X 192GB — ≈443.8 tok/s Q4 est.
• H100 80GB SXM5 — ≈280.5 tok/s Q4 est.
• Gaudi 3 128GB — ≈274.3 tok/s Q4 est.
• A100 80GB SXM4 — ≈154.05 tok/s Q4 measured
• RTX 5090 32GB — ≈150.0 tok/s Q4 est.
• RTX 4090 24GB — ≈84.4 tok/s Q4 est.
• RTX 4090D 24GB (China) — ≈84.4 tok/s Q4 est.

All GPUs for Qwen2.5-7B-Instruct →

Other models for the H200 141GB SXM5

• Qwen3-0.6B — ≈3818.2 tok/s Q4 est.
• gemma-3-1b-it — ≈3054.5 tok/s Q4 est.
• Llama-3.2-1B-Instruct — ≈2545.5 tok/s Q4 est.
• Qwen3-1.7B — ≈1527.3 tok/s Q4 est.
• Qwen3-30B-A3B — ≈1018.2 tok/s Q4 est.
• Qwen3-Coder-30B-A3B-Instruct — ≈1018.2 tok/s Q4 est.
• GLM-4.7-Flash — ≈1018.2 tok/s Q4 est.
• Qwen3-30B-A3B-Instruct-2507 — ≈1018.2 tok/s Q4 est.

All models on the H200 141GB SXM5 →