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Can H100 80GB SXM5 run Mistral-7B-Instruct-v0.3?

NVIDIA · 80 GB HBM3 · 3350 GB/s bandwidth · Mistral · 7.2B · model ctx up to 32K

Yes — the H100 80GB SXM5 (80 GB HBM3) can run Mistral-7B-Instruct-v0.3. At Q4 with the default 8K context it needs ≈ 6.4 GB VRAM (weights 3.96 GB + KV cache 1.44 GB + 1 GB runtime overhead), which fits within 80 GB. Decode at Q4/8K: ≈ 296.1 tok/s (estimated, batch 1). FP16 (≈ 16.84 GB) also fits, at ≈ 81.4 tok/s (estimated). Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

QuantContextVRAM neededFits?tok/s (decode)
Q44K5.68 GBYes296.1 est.
Q48K default6.4 GBYes296.1 est.
Q432K10.72 GBYes296.1 est.
FP164K16.12 GBYes81.4 est.
FP168K default16.84 GBYes81.4 est.
FP1632K21.16 GBYes81.4 est.

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

QuantWeightsKV cacheOverheadTotal neededH100 80GB SXM5 VRAM
Q43.96 GB1.44 GB1 GB6.4 GB80 GB
FP1614.4 GB1.44 GB1 GB16.84 GB80 GB

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