Can H100 80GB SXM5 run Qwen3.5-397B-A17B?

NVIDIA · 80 GB HBM3 · 3350 GB/s bandwidth · Alibaba · 397.0B (active 17.0B) · MoE · model ctx up to 256K

No — Qwen3.5-397B-A17B at Q4 needs ≈ 221.05 GB even at 4K context, beyond the H100 80GB SXM5's 80 GB HBM3. It would only run with heavy CPU/disk offload. Decode at Q4/8K: ≈ 46.2 tok/s (estimated, batch 1). FP16 needs ≈ 798.4 GB — does not fit on this card. Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.

Fit & speed by quant and context

Quant	Context	VRAM needed	Fits?	tok/s (decode)
Q4	4K	221.05 GB	No	46.9 est.
Q4	8K default	222.75 GB	No	46.2 est.
Q4	32K	232.95 GB	No	42.3 est.
FP16	4K	796.7 GB	No	—
FP16	8K default	798.4 GB	No	—
FP16	32K	808.6 GB	No	—

Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

Quant	Weights	KV cache	Overhead	Total needed	H100 80GB SXM5 VRAM
Q4	218.35 GB	3.4 GB	1 GB	222.75 GB	80 GB
FP16	794.0 GB	3.4 GB	1 GB	798.4 GB	80 GB

Other GPUs that run Qwen3.5-397B-A17B

No catalog GPU fully fits Qwen3.5-397B-A17B at Q4/8K — see the model page for offload estimates.

All GPUs for Qwen3.5-397B-A17B →

Other models for the H100 80GB SXM5

• MiniCPM5-1B — ≈1973.9 tok/s Q4 est.
• Qwen3.5-2B — ≈1065.9 tok/s Q4 est.
• GLM-4.7-Flash — ≈710.6 tok/s Q4 est.
• Qwen3-30B-A3B-Instruct-2507 — ≈710.6 tok/s Q4 est.
• Qwen3-Next-80B-A3B-Instruct — ≈710.6 tok/s Q4 est.
• Qwen3-Coder-Next — ≈710.6 tok/s Q4 est.
• Qwen3.5-35B-A3B — ≈710.6 tok/s Q4 est.
• Qwen3.6-35B-A3B — ≈710.6 tok/s Q4 est.

All models on the H100 80GB SXM5 →