Yes — the Ryzen AI Max+ 395 128GB (96 GB LPDDR5X) can run Devstral-Small-2-24B-Instruct-2512. At Q4 with the default 8K context it needs ≈ 19.0 GB VRAM (weights 13.2 GB + KV cache 4.8 GB + 1 GB runtime overhead), which fits within 96 GB. Decode at Q4/8K: ≈ 5.7 tok/s (estimated, batch 1). FP16 (≈ 53.8 GB) also fits, at ≈ 1.6 tok/s (estimated). Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.
Fit & speed by quant and context
Quant
Context
VRAM needed
Fits?
tok/s (decode)
Q4
4K
16.6 GB
Yes
5.7est.
Q4
8K default
19.0 GB
Yes
5.7est.
Q4
32K
33.4 GB
Yes
5.7est.
FP16
4K
51.4 GB
Yes
1.6est.
FP16
8K default
53.8 GB
Yes
1.6est.
FP16
32K
68.2 GB
Yes
1.6est.
Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).
VRAM breakdown at 8K context
Quant
Weights
KV cache
Overhead
Total needed
Ryzen AI Max+ 395 128GB VRAM
Q4
13.2 GB
4.8 GB
1 GB
19.0 GB
96 GB
FP16
48.0 GB
4.8 GB
1 GB
53.8 GB
96 GB
Other GPUs that run Devstral-Small-2-24B-Instruct-2512