Yes — the Ryzen AI Max+ 395 128GB (96 GB LPDDR5X) can run Qwen3.5-27B. At Q4 with the default 8K context it needs ≈ 16.53 GB VRAM (weights 14.85 GB + KV cache 0.68 GB + 1 GB runtime overhead), which fits within 96 GB. Decode at Q4/8K: ≈ 5.1 tok/s (estimated, batch 1). FP16 (≈ 55.67 GB) also fits, at ≈ 1.4 tok/s (estimated). Estimates come from memory-bandwidth math; rows tagged measured override estimates. Relative ranking is more reliable than absolute tok/s. Methodology.
Fit & speed by quant and context
Quant
Context
VRAM needed
Fits?
tok/s (decode)
Q4
4K
16.19 GB
Yes
5.1est.
Q4
8K default
16.53 GB
Yes
5.1est.
Q4
32K
18.55 GB
Yes
5.1est.
FP16
4K
55.34 GB
Yes
1.4est.
FP16
8K default
55.67 GB
Yes
1.4est.
FP16
32K
57.7 GB
Yes
1.4est.
Fits = weights + KV(ctx) + 1 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).