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Can MacBook Neo A18 Pro 8GB run Qwen2.5-72B-Instruct?

Apple · 8 GB LPDDR5X · 60 GB/s bandwidth · Alibaba · 72.7B · model ctx up to 128K

❌ No — Qwen2.5-72B-Instruct Q4 needs 42.96 GB, card only has 8 GB
VRAM: 42.96 GB needed of 8 GB
FF · No FitComposite score: VRAM headroom × 0.5 + tok/s speed × 0.5. Q4 @ 8K context.
METAL
Your GPU won't fit Qwen2.5-72B-Instruct, but runs these similar models: Qwen2.5-7B-Instruct, gemma-4-E2B-itor☁️ Rent on RunPod from ~$0.50/hr
Estimates from memory-bandwidth formula; rows marked "measured" override. Methodology.

Fit & speed by quant and context

QuantContextVRAM neededFits?tok/s (decode)
Q44K42.96 GBNo
Q48K default44.21 GBNo
Q432K51.71 GBNo
FP164K147.65 GBNo
FP168K default148.9 GBNo
FP1632K156.4 GBNo

Fits = weights + KV(ctx) + 0.5 GB overhead ≤ 95% of VRAM. Measured anchors are context-agnostic; the fit verdict is recomputed per context. A missing tok/s means the model is far beyond this card (offload-only territory).

VRAM breakdown at 8K context

QuantWeightsKV cacheOverheadTotal neededMacBook Neo A18 Pro 8GB VRAM
Q440.71 GB2.5 GB0.5 GB44.21 GB8 GB
FP16145.4 GB2.5 GB0.5 GB148.9 GB8 GB

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